Welcome to CircDA

Circal RNAs (cirRNAs) are an important category of non-coding RNAs which range from 200 nucleotides to multiple kilobases in length, with little. CircRNAs are widely expressed in diverse eukaryotic species and are characterized by covalently closed RNA loops through backsplicing events. Increasing evidence has highlighted the critical roles of circRNAs in plenty of diseases development and progression. Here, we constructed CircDA by integrating comprehensive experimentally supported and predicted circRNA-disease associations curated from manual literatures and other resources. The developments in CircDA include (I) over 40-fold ncRNA-disease associations enhancement compare to the previous version; (II) integrating experimentally supported circRNA-disease associations; (III) providing regulatory relationship among ncRNA, mRNA and miRNA; (IV) mapping disease name to the Disease Ontology and Medical Subject Headings (MeSH); (V) providing a confidence score for each ncRNA-disease association.